Mr. A, a 54-year-old Caucasian man employed as an office manager, was found to have a positive skin test for purified protein derivative of tuberculin and was given prophylactic isoniazid, 300 mg/day. A chest X-ray was normal. He reported no drug or alcohol abuse. He smoked a pack of cigarettes a day.
Two weeks after beginning isoniazid treatment, Mr. A drove himself to a morning business appointment. There he appeared to have difficulty thinking and was thought to have a mental problem. He was taken to his psychiatrist and then to the emergency department. His wife later confirmed that his thinking was clear before he left home, although she had noticed episodes of slight confusion lasting a few minutes each the previous day.
A physical examination revealed no acute abnormalities. Deep tendon reflexes were brisk and slightly more on the right side. Mr. A moved his extremities symmetrically. His gait and coordination were normal except for a slight clumsiness. A chest X-ray, a CBC, a metabolic profile, a urinalysis, a drug screen, a computerized tomographic scan of his head, and measures of thyroid-stimulating hormone, rapid plasma reagent, and arterial blood gases were unremarkable.
가능성이 높은 이유로 생각되는 것은?
pyridoxine (vitamin B6) deficiency.
(다른 유형의 문제)
A 30 year old man receiving a 6 month course of isoniazid after being exposed to tuberculosis and develping a positive PPD skin test. 결핍되기 쉬운 nutrient는?
